CoMCoR

The Impact of Comorbidities on Colorectal Cancer Treatment and Time to Surgery: A High-Resolution Population-Based Study

Comorbidities and colorectal cancer

Background and objectives

Cancer recurrence and disease-free survival are usually analysed in clinical trials, enrolling healthier and younger patients than the general cancer population, thus being unrepresentative for the real-world where comorbid elderly patients are the group with higher cancer incidence rates. As part of the effort to evaluate real-world comparative effectiveness research and cancer survival outcomes, the population-based cancer registries of Granada and Girona identified all incident cases (n=1,061) from colorectal cancer patients. Clinical information from patients diagnosed during the year 2011 and follow-up until December 31st, 2016, was collected as part of a High-Resolution European study (HIGHCARE project-Eranet TRANSCAN). Patients and tumour characteristics, type of treatment, and comorbidities were drawn from medical records.

The main objective of the proposal is to describe the pattern of comorbidities by patient, tumour and healthcare factors and to investigate the extent to which comorbidities influence time from diagnosis to cancer surgical treatment and cancer treatment.

The investigation will contribute to promote policy action aiming to reduce cancer survival disparities.


Apps

- CoMCoR: Comorbidities’ frequency, distribution, and risk among colorectal cancer patients: A population-based high-resolution study in Spain.

- TiMSurG: A ShinyApp tool to evaluate time to surgery among colorectal cancer patients with comorbidities: A population-based high-resolution study in Spain.



About us

Non‐Communicable and Cancer Epidemiology Group, Biomedical Research Institute of Granada (ibs.Granada)

Carlos III Institute of Health, Grant/Award Number: CP17/002026

We are a team with expertise in Epidemiology, Biostatistics, Public Health, Social Sciences and Mathematics.

We develop our work at the Biomedical Research Institute of Granada, based at the Granada Cancer Registry, placed at the Andalusian School of Public Health.

Miguel Ángel Luque Fernández, MA, MPH, MSc, PhD

Senior Scientific Researcher of Epidemiology and Biostatistics
Miguel Servet I Award, Carlos III Institute of Health
Ibs.Granada, Andalusian School of Public Health.
Cuesta del Observatorio, 4, 18080
Granada, Spain
Hugo Academic Webpage

Visitor Scientist, Department of Epidemiology,
TH Chan Harvard School of Public Health, Boston, MA, U.S.A.
HSPH Webpage

Assistant Professor of Epidemiology and Biostatistics (Honorary)
Department of Non-Communicable Disease Epidemiology
London School of Hygiene and Tropical Medicine, London, U.K.
LSHTM Academic Webpage

Biomedical Network Research Centers of Epidemiology and Public Health (CIBERESP), ISCIII, Madrid, Spain.

Tutorials Link to Epidemiological and Statistical tutorials

twitter @watzilei

git @migariane

email miguel.luque.easp at juntadeandalucia.es


git

Elena Salamanca Fernández, MSc

Research Assistant of Environmental Epidemiology. PhD student.

Biomedical Research Institute of Granada, ibs Granada. University of Granada. Andalusian School of Public Health. Cuesta del Observatorio, 4, 18080 Granada, Spain

Biomedical Network Research Centers of Epidemiology and Public Health (CIBERESP), ISCIII, Madrid, Spain

Research Support Unit. San Cecilio Clinical Hospital, Granada.

Pollution Surveillance and Control Laboratory. Environment and Water Agency, Ministry of Environment, Junta de Andalucía.

twitter @E_salamanca

email elena.salamanca.easp at juntadeandalucia.es


CIBER